Dr. Sheffield's Anti-Itch Cream with Histamine Blocker 1.25 oz — Diphenhydramine 2% + Zinc, Fast-Acting Relief for Bites & Rashes

Dr. Sheffield's Extra Strength Anti-Itch Cream is a compact topical cream formulated with a histamine blocker and skin protectant to help temporarily ease itching and dry oozing from minor rashes and insect bites.

Made in the USA, this 1.25-ounce tube combines diphenhydramine HCl (a topical antihistamine) and zinc acetate (a skin protectant) in a fast-acting formula designed for short-term use on minor skin irritations. The non-greasy cream is intended for targeted application where itching, minor pain, or weeping from poison ivy, oak, and sumac are present. It's travel-friendly and convenient for first-aid kits, outdoor excursions, and everyday home use.

How quickly will I notice relief after applying the cream?

Many users feel cooling or soothing sensation within minutes as the active ingredients begin to address surface-level irritation. Peak effect varies by severity of the rash and skin type, but the formula is designed for prompt topical action.

• Contains diphenhydramine HCl 2% for topical antihistamine support
• Includes zinc acetate 0.1% to protect and help dry oozing areas
• Non-greasy texture absorbs quickly for targeted relief

What types of skin problems is this cream made for?

This cream is intended for temporary relief of itching and minor pain from common skin irritations. It is commonly used for insect bites, minor burns, sunburn discomfort, rashes, and the oozing or weeping associated with poison ivy, oak, and sumac.

• Insect bites and stings
• Minor burns and sunburn-related discomfort
• Rashes and skin irritations that cause itching
• Helps dry oozing from poison ivy, oak, and sumac

How should I apply the Dr. Sheffield's Anti-Itch Cream?

Apply a thin layer directly to the affected area and rub in gently until absorbed. Use only as directed on the product packaging; avoid contact with eyes and mucous membranes and do not use on deep or puncture wounds.

• Clean and dry the skin before application
• Apply thinly to the irritated area; do not bandage tightly
• Store at room temperature and replace cap securely after use

Are there precautions or limitations I should know about?

Because this product contains a topical antihistamine and a skin protectant, follow label directions and consult a healthcare provider if symptoms persist or worsen. Avoid prolonged use on large areas of skin, and keep out of reach of children.

• Contains diphenhydramine HCl 2% and zinc acetate 0.1%
• Not for long-term use without professional guidance
• Store away from children and avoid eye contact

Who this is for: Dr. Sheffield's Extra Strength Anti-Itch Cream suits anyone needing a compact, over-the-counter topical option for short-term relief of itching and minor skin oozing. It's practical for campers, parents, first-aid kits, and home medicine cabinets when you want a targeted cream with both an antihistamine and a skin-protecting ingredient. If you have severe, widespread, or persistent skin conditions, seek professional medical advice before use.

Ingredients

Cetyl Alcohol, Diazolldinyl Urea, Methylparaben, PEG 20 Sterate, Proplylene Glycol, Proplyparaben, Purified Water